Effect of bromocriptine on estrogen-induced rat prolactinoma.
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولThe effect of octreotide and bromocriptine on expression of a pro-apoptotic Bax protein in rat prolactinoma.
It is well established that disruption of apoptosis may lead to tumor initiation, progression or metastasis. It is also well documented that many anticancer drugs induce apoptosis. In the earlier studies, the dopamine D2 receptor agonist bromocriptine (BC) and somatostatin analog octreotide (OCT) were found to inhibit the growth of the estrogen-induced rat prolactinoma. Our previous investigati...
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Rats with estrogen-induced prolactin-producing pituitary adenoma (E2-PRLoma) have been employed as an animal model of human PRL-producing pituitary adenoma in a large number of studies. Presently, we found that long-term administration of estrogen to SD rats resulted in the development of E2-PRLomas, some of which included multi-hormone producing nodules. We herein report results of histopathol...
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ژورنال
عنوان ژورنال: Neurologia medico-chirurgica
سال: 1987
ISSN: 0470-8105,1349-8029
DOI: 10.2176/nmc.27.475